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Tuesday 01 November 2005

Ziprasidone overdose: cardiac safety.

By: Insa Gomez FJ, Gutierrez Casares JR.

Actas Esp Psiquiatr 2005 Nov-Dec;33(6):398-400

Ziprasidone is a neuroleptic drug recently sold in Spain. According to its profile of receptors it is considered an atypical or second generation antipsychotic agent. Its use has been associated to increase of the QT interval, which might trigger potentially lethal ventricular arrhythmia. We present a case of overdose with moderate doses of the drug, in which there were no important changes in the QT interval. A review of the cases of overdose published up to now was also done.

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